June 19-22, 2024

10th Biennial Meeting of the International Society for Gastrointestinal Hereditary Tumours

AXA Convention Center

Avinguda Diagonal, 547, Barcelona, Spain

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#InSiGHT2024

Welcome

Dear Colleagues, Dear Friends,

On behalf of the Board of Directors and the Program Committee it is a great pleasure to invite you to the 2024 Insight Biennial Conference to be held in Barcelona at 19th-22nd June 2024.

This conference, which focusses on the worldwide improvement of care of patients and families with any hereditary condition resulting in gastrointestinal tumors, is a great opportunity and challenge. We aim to make this a great scientific meeting that attracts clinical and research experts in the field, including PhD students and other early career scientists and physicians.

The Program Committee has been working hard to put together a vibrant and comprehensive program for the meeting securing the participation of internationally acknowledged invited experts to address hot topics on key areas in Fundamental, Translational and Clinical Science in sessions with invited speakers and the best peer-reviewed abstracts as oral communications. Workshops will allow lively debating. We will also have the opportunity to listen the voice of patients critical to adequately design our care and our research.

Selected topics include among others: Mutational signatures and somatic evolution in normal tissue; the use of artificial intelligence (AI) in Digital pathology and Endoscopies; and monogenetic defects and Polygenic Risk Scores. Regarding clinical science we will be addressing surgical challenges as well as controversies in surveillance and testing in pediatric and adult settings. Issues on colorectal, gynecological, gastric and biliopancreatic neoplasms will also be discussed. Also chemoprevention, vaccines and lifestyle modification will be tackled. Finally, we have joined forces with the European Society of Gastrointestinal Endoscopy to organize a pre-meeting educational event.

A scientific congress is not just a series of lectures or debates delivered from a podium. There is the social interaction, meeting old friends and making new acquaintances which may turn to become lifelong, discussing a project over a coffee, inviting colleagues to spend time in our unit. Especially for trainees, a congress represents the unique opportunity to meet renowned professionals and establish connections that can lead to new professional opportunities. In this regard, we have done our best to promote the active participation of the young people hoping to help providing effective enduring mentorship to the next generation of physicians, health professionals and scientists.

As Chairpersons of Insight we are very happy and honored to welcome all of you in Barcelona

next June to share and learn the most up to date evidence in our specialty and to enjoy networking with your friends and colleagues.

Kind regards, also on behalf of the InSiGHT Scientific Committee,

CONFERENCE DIRECTORS

CORE SCIENTIFIC COMMITTEE

Prof. dr. Nicoline Hoogerbrugge

MD, PhD, internist-cancer geneticist. Radboud University, Nijmegen, Netherlands

Dr. Gabriel Capellá

MD, PhD, Catalan Institute of Oncology- IDIBELL, cancer geneticist,  L’Hospitalet de Llobregat, Spain

Dr. Francesc Balaguer

MD, PhD, gastoenterologist. Hospital Clinic, Barcelona, Spain

Prof. dr. Marjolijn Ligtenberg

PhD, molecular geneticist.  Radboud University, Nijmegen, Netherlands

19:00-21:00
Pre-InSiGHT meeting for patients and patient representatives with Lynch syndrome or polyposis

Chairs:
Nicoline Hoogerbrugge, Radboud university medical center, Nijmegen, The Netherlands
Gabriel Capellá, Catalan Institute of Oncology & Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Spain

19:00
What you need to know about the colonoscopy

Francesc Balaguer, Hospital Clínic Barcelona, Spain

19:20
Different Lynch genes have different hereditary risks: PMS2 is the odd out

Brandie Leach, Hereditary Cancer Medical Affairs, Exact Sciences, Cleveland, Ohio, USA

19:40
Life after colectom

Toni T. Seppälä, Helsinki University Hospital, Helsinki, Finland

20:00
Promising news: Immune therapy in cancer treatment of patients with Lynch syndrome

Dr. Judith Balmaña, Vall d’Hebron, Institute of Oncology (VHIO), Barcelona, Spain

20:30
Questions from the audience
21:00
Closing remarks
08:25-12:20
ESGE/ESDO postgraduate course: “Advances in GI endoscopy and immunotherapy in the management of hereditary GI syndrome”
08:00-08:30
ESGE/ESDO postgraduate course registration
08:25-08:30
Welcome message
08:30-09:30
SESSION 1: Tips and Tricks for colonoscopy in high-risk conditions

• Surveillance of the colon in Lynch Syndrome: Tips and tricks
• Surveillance of the pouch/rectum in FAP: Tips and tricks
• Management of SPS: How to diagnose and treat SSLs

09:30-10:30
SESSION 2: Tips and tricks for upper endoscopy in high-risk conditions

• Prevention of gastric cancer: Tips and tricks for a high-quality upper GI endoscopy
• Prevention of gastric cancer in FAP
• Managing CDH1/CTNNA1B patients

10:30-11:00
Coffee Break
11:00-11:40
SESSION 3: Surveillance of the duodenum in high-risk conditions

• How to deal with intestinal polyps in Peutz Jeghers?
• Management of duodenal polyposis in FAP

11:40-12:20
SESSION 4: New advances in immunotherapy in GI cancers

• Immunotherapy in colorectal cancer
• Immunotherpay in upper GI cancer

12:00-13:00
Congress Registration
13:00-13:20
Welcome and Announcements

Nicoline Hoogerbrugge, Radboud University, Nijmegen, The Netherlands
Gabriel Capellá, Catalan Institute of Oncology & Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Spain

13:20-15:10
Session 1 - Translational science
13:20-13:45
Use of AI in Endoscopies

Robert Hüneburg, Bonn University Hospital, Bonn, Germany

13:45-14:10
Use of AI colorectal cancer - its application to GI hereditary tumors

Francesco Ciompi, Radboud University Medical Centre, Nijmegen, The Netherlands

14:10-14:55
Debate: Strategies to find all patients with hereditary cancer

Stefan Aretz, University of Bonn Medical Center, Bonn, Germany
Judith Balmaña, Vall d’Hebron Institute of Oncology (VHIO), Barcelona, Spain

14:55-15:25
Abstract Presentations 1
15:25-15:55
Coffee Break
15:55-17:50
Session 2 - Translational Science
15:55-16:20
Microbiome and (risk of) hereditary GE cancer

Annemarie Boleij, Radboud University Medical Centre, Nijmegen, The Netherlands

16:20-17:50
Abstract Presentations 2
17:50-18:00
Adjourning
20:00
Welcome reception

Location: Conference Venue

08.30-10.05
Session 3 - Fundamental Science
08:30-08:55
New genetic aspects of Lynch syndrome

Marjolijn Ligtenberg, Radboud university medical center, Nijmegen, The Netherlands

08:55-09:20
New genes for polyposis

Laura Valle, Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Spain

09:20-09:50
Abstract Presentations 3
09:50-10:05
Flashtalks
10:05-11:05
Coffee Break + poster session A
11:05-12.25
Session 4 - Fundamental Science
11:05-11:30
Mutational signatures (somatic evolution in normal tissue)

Gene Koh, University of Cambridge, Cambridge, United Kingdom

11:30-11:55
Genetics in hamartomatous Polyposis

Nicoline Hoogerbrugge, Radboud University Medical Centre, Nijmegen, The Netherlands

11:55-12:25
Abstract Presentations 4
12:25-13:10
Debate: Surveillance in moderate risk genes

Sonia Kupfer, University of Chicago, Chicago, United States
Andrew Latchford, St Mark's Hospital, London, United Kingdom

13:10-14:10
Lunch Break
14.10-16:00
Session 5 - Clinical Science
14:10-14:35
Endoscopic surveillance in GI syndrome

Francesc Balaguer, Hospital Clínic Barcelona, Spain

14:35-15:00
Surveillance in children with FAP

Warren Hyer, St Marks Hospital & Chelsea and Westminster Hospital, London, United Kingdom

15:00-16:00
Abstract presentations 5
16:00-16:30
Coffee Break
16:30-17:15
Debate: New-born testing on hereditary cancer genes

Héctor Salvador, Hospital Sant Joan de Déu, Barcelona, Spain
Ingrid Winship, University of Melbourne & Royal Melbourne Hospital, Melbourne, Australia

17:15-18:15
Abstract Presentations 6
18:15-18:20
Adjourning
20:00
Get together meeting
08:30-10.05
Session 6 - Clinical Science
08:30-08:55
Surgery in Lynch syndrome and polyposis

Gabriela Möslein, Academic Hospital of the University of Düsseldorf, Duisburg, Germany

08:55-09:20
Recent advances in Immunotherapy for GI and gynecological tumors

Pilar Barretina, Catalan Institute of Oncology & Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Spain

09:20-09:50
Abstract Presentations 7
09:50-10:05
Flashtalks
10:05-11:05
Coffee Break + poster session B
11:05-12.25
Session 7 - Clinical Science
11:05-11:30
Pancreas surveillance in high-risk individuals

Diane Simeone, NYU Pancreatic Cancer Center, New York, United States

11:30-12:30
Abstract Presentations 8
12:30-13:15
Debate: Early onset pancreatic cancer

Toni T. Seppälä, Helsinki University Hospital, Helsinki, Finland
Eileen M. O’Reilly, Memorial Sloan Kettering Cancer Center, New York, United States

13:15-14:15
Lunch Break
14:15-16.05
Session 8 - Clinical Science
14:15-14:40
Endometrial cancer in hereditary cancer syndromes

Emma J. Crosbie, St Mary's Hospital, Manchester, United Kingdom

14:40-15:05
Ovarian cancer in hereditary cancer syndromes

Neil Ryan, St Mary's Hospital, Manchester, United Kingdom

15:05-16:05
Abstract Presentations 8
16:05-16:35
Coffee Break
16:35-17:20
Debate: Strategies on endometrial and ovarian cancer in Lynch syndrome

Joanne A. de Hullu, Radboud University Medical Center, Nijmegen, he Netherlands
Anne van Altena, Radboud University Medical Centre, Nijmegen, The Netherlands

17:20-18:20
Abstract Presentations 9
18:20-18:25
Adjourning
20:00
Congress dinner

Venue: Terraza Miramar
Address: Plaça de l’Armada, s/n, Montjüic, Sants-Montjuïc, 08038 Barcelona (Limited Seats - Registration Required)

08:30-10:20
Session 9 | Clinical Science
08:30-08:55
Lifestyle and risk of hereditary cancer

Aung Ko Win, University of Melbourne Centre for Cancer Research, Melbourne, Australia

08:55-09:20
Surveillance frequency in familial colorectal cancer

Veerle Coupe, VU Medical Centre, Amsterdam

09:20-10:20
Abstract Presentations 10
10:20-10:50
Coffee Break
10:50-12:25
Session 10 - Clinical Science
10:50-11:15
Vaccines for Lynch syndrome

Eduardo Vilar, MD Anderson Cancer Center, Houston, Texas, United States

10:15-11:40
Chemoprevention of hereditary GI cancer

John Burn, Professor of Clinical Genetics, Cancer Prevention, Newcastle University, Newcastle, United Kingdom

12:40-12:25
Debate: Differences in colorectal cancer management

Joanne Ngeow, Cancer Genetics Service, National Cancer Centre Singapore
Finlay Macrae, The Royal Melbourne Hospital, Melbourne, Australia

12:25-13:25
Best Oral Communications
13:25-13:40
Concluding remarks

Nicoline Hoogerbrugge, Radboud University, Nijmegen, The Netherlands
Dr. Gabriel Capellá, Catalan Institute of Oncology & Bellvitge Biomedical Research Institute (IDIBELL), L’Hospitalet de Llobregat, Spain

Overview

Meeting overview

PROGRAMME

Meeting programme

INFORMATION

General information & deadlines

Registration

Meeting registration

Registration Fees

ABSTRACT CONTEST

The abstract contest is closed.

10 October 2023

Abstract Submission Opening

21 January 2024

Deadline to submit your abstract(s)

Mid-March 2024

Notifications to the abstract submitters

1 April 2024

The abstract presenting author must be registered for the conference at the latest by this date

Why to submit your abstract?

Share your research with your peers and leaders in the field.
Opportunity to discuss your controversial clinical cases with experts.
Opportunity to be selected for Free Paper sessions.
All accepted abstracts displayed as Posters during the meeting.
Best abstract and best poster awards!

ACCOMODATION

Booking of accommodation for INSIGHT2024 is now open!

Sponsors

UNDER THE AUSPICE OF

CME CREDITS

The 10th Biennial Meeting of the International Society for Gastrointestinal Hereditary Tumours ill apply to the European Accreditation Council for Continuing Medical Education  (EACCME®).

Frequently Asked Questions

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